Programme (Day 2: 8 Nov)

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08:45 – 09:15 Opening Ceremony
09:15 – 10:00 Keynote Lecture
Moderator: Wing-hong Kwan
Proton versus Photon Radiotherapy for Head and Neck Cancer – The Journey to a New Standard of Care
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Steven J. Frank

Executive Director, Particle Therapy Institute
Department of Radiation Oncology, Division of Radiation Oncology
The University of Texas MD Anderson Cancer Center
USA

Steven J. Frank, MD, is an endowed tenured professor of Radiation Oncology, holds the Bessie McGoldrick Professorship in Clinical Research, and is a fellow of the ABS, ACR, and ASTRO. Dr. Frank is the Executive Director of the Particle Therapy Institute and Deputy Head of Strategy for the Division of Radiation Oncology. Dr. Frank is amongst the first, if not the first, to use IMPT to treat head and neck tumors, and he is the Principal Investigator of an NIH/NCI/Hitachi-sponsored multi-institutional Phase II/III randomized trial in advanced stage oropharyngeal cancer that compares outcomes after chemoradiation given by IMRT versus IMPT.

Dr. Frank has over 300 peer-reviewed publications, has authored many book chapters and has recently published the first textbook on Proton Therapy. Dr. Frank's lab is studying the biologic enhancement factor of proton therapy and FLASH radiotherapy for both head and neck and prostate cancer, as well as MRI-Assisted Radiosurgery (MARS) as the next generation of prostate brachytherapy. Dr. Frank's expertise in MRI radiotherapy has led to the development and FDA approval of multiple novel positive-contrast implantable markers for use in MRI-guided LDR and HDR prostate brachytherapy and external beam radiation therapy.

As founder of the company, C4 Imaging, Dr. Frank has developed the MRI marker technology at MD Anderson, has been granted 31 national and international patents, developed three FDA-approved products and has established MRI-Assisted Radiosurgery (MARS) at MD Anderson for the treatment of prostate cancer. He has funding from the NIH, the Prostate Cancer Foundation, the Texas Ignition Fund, Hitachi and MD Anderson, and he has also raised multiple rounds of private equity financing to advance the C4 technology. Dr. Frank has served as the past President and Chairman of the Board of the American Brachytherapy Society and is the 2023 recipient of the Ulrich Henschke Award, the highest honor awarded by the ABS on a practitioner of brachytherapy.

Dr. Frank has served as the chair for the head and neck oral boards for seven years and is currently serving on the Radiation Oncology Board of Trustees for the American Board of Radiology.

Steven Frank (USA)
10:00 – 10:30 Coffee Break, Exhibition and e-Poster Viewing
10:30 – 12:30 Session 1A (Physics): Imaging in Proton Therapy
Moderators: Taku Inaniwa and Ed Wu
Imaging in Proton Therapy
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Chia-ho Hua

Director of Medical Physics Research
Department of Radiation Oncology
St. Jude Children's Research Hospital
USA

Dr. Chia-ho Hua earned his PhD in Biomedical Engineering from The University of Michigan in Ann Arbor, where he studied radionuclide tomographic imaging. He received postdoctoral and clinical training in therapeutic medical physics at Memorial Sloan-Kettering Cancer Center in New York. He was certified by the American Board of Radiology in Therapeutic Medical Physics in 2004. Dr. Hua joined the faculty at St. Jude in 2005 and is currently a Full Member and the Director of Medical Physics Research. His research aims to improve proton therapy targeting accuracy, advanced imaging for precision radiation oncology, and predictive modeling for radiation effects in children. Dr. Hua is also the Physics Committee Chair of the Children's Oncology Group Radiation Oncology Discipline and the steering committee member of the Pediatric Normal Tissue Effects in the Clinic (PENTEC) international consortium. In 2023, Dr. Hua was elected as a Fellow of the American Association of Physicists in Medicine (FAAPM).

Chia-ho Hua (USA)
Image Guidance for High Precision Particle Therapy
Yoshikazu Maeda (Japan)
AI-based Real-time Tumor Tracking Proton Therapy
Toshiyuki Terunuma (Japan)
MRI-guidance in Proton Therapy
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Leon Ho

Medical Physicist I
Medical Physics Department
HKSH Eastern Medical Centre
Hong Kong

Dr. Leon Chin Chak HO received his B.Eng. and Ph.D. degrees from The University of Hong Kong (HKU) in 2011 and 2016, respectively. Following his doctoral studies, he joined Hong Kong Sanatorium & Hospital (HKSH) Medical Group as a medical physicist. After receiving his board-certification in radiation oncology physics from the Hong Kong Institution of Physicists in Medicine (HKIPM), Dr. Ho was appointed as an honorary assistant professor by the Department of Diagnostic Radiology at The University of Hong Kong. His research interests include MR-guidance in radiation therapy, as well as the development of MR-integrated workflows in radiotherapy and proton therapy.

Leon Ho (Hong Kong SAR)
12:30 – 14:00 Lunch Break
14:00 – 16:00 Session 2A (Physics): High Precision Proton Therapy
Moderators: John Wong and Jing Cai
Treatment Planning for High Precision Proton Therapy
Martin Bues (USA)
Treatment of Small Target in Proton Therapy
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Chen-yu Chou

Senior Medical Physicist
Department of Radiation Oncology
Chang Gang Memorial Hospital, Linkou branch
Taiwan

Chen-Yu Chou is a highly skilled medical physicist with over a decade of experience in radiation therapy. He holds an M.S. in Medical Technology and Engineering and is currently pursuing a doctoral degree. Certified as a radiotherapist, radiation protection specialist, and medical physicist, Chou has been a key member of Linkou Chang Gung Memorial Hospital since 2014. He leads quality assurance for a wide range of radiotherapy systems, including linear accelerators, proton systems, brachytherapy, and CT. Chou specializes in developing advanced treatment plans for various cancer types, including photon and proton therapy, and plays a key role in the proton stereotactic radiosurgery program. His research interests include planning optimization, MRI simulation, and proton therapy, resulting in numerous publications and presentations. An invited speaker at conferences, Chou has held leadership roles as Supervisor of the Society of Medical Physics and served as an Oral Examiner for the Medical Physicist License Examination in Taiwan.

Chen-yu Chou (Taiwan)
Adaptive Proton Therapy
Dayananda Sharma (India)
Biology and Clinical Relevance of FLASH
G-one Ahn (Korea)
16:00 – 16:30 Coffee Break, Exhibition and e-Poster Viewing
16:30 – 18:00 Session 3A (Physics): Oral Presentation
Moderators: Chia-ho Hua and Kimi Yang
18:00 – 18:15 Closing Remarks
10:30 – 11:30 Session 1B (Clinical): Updates on Clinical Management
Moderators: Kyung-hwan Kim and Rico Liu
Lung Cancer
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Ramesh Rengan

Peter Wootton Professor and Chair
Department of Radiation Oncology, UW Medicine
SVP, Fred Hutchinson Cancer Center
USA

Dr. Ramesh Rengan is currently the Peter Wootton Chair and Professor in the Department of Radiation Oncology at the University of Washington School of Medicine and the Senior Vice President and Director in Radiation Oncology Division at the Fred Hutchinson Cancer Center. He also holds a joint appointment as faculty of the Integrated Immunotherapy Research Center, Fred Hutchinson Cancer Center. His clinical interests include thoracic malignancies, melanomas (including ocular melanoma), renal cell carcinoma, and prostate cancer. Additionally, he has clinical expertise in the use of proton beam therapy in the management of localized and locally advanced solid tumors. His research interests include approaches to improve the therapeutic ratio in solid tumors to ionizing photon or proton radiation, pre-clinical and clinical strategies to utilize radiation to trigger an anti-tumor immune response in patients with advanced solid malignancies. He also has an interest in healthcare disparities and expanded access to radiation treatment in low-resource environments and Photon- and Proton based radiation regimens to trigger an immune response to augment immunotherapeutic platforms in solid malignancies including NSCLC, melanoma, lymphoma, and renal cell carcinoma.

Ramesh Rengan (USA)
Liver Cancer
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Hideyuki Sakurai

Professor and Chairman
Department of Radiation Oncology, University of Tsukuba
Director
Proton Beam Therapy Center, University of Tsukuba Hospital
Japan

Hideyuki Sakurai received the medical degree in Gunma University in 1988 and the PhD degree in 1996. In 1992, he served as visiting scientist in Medical Research Council at Cambridge University in UK.

He is currently a professor and Chairman in Radiation Oncology, Institute of Medicine, University of Tsukuba. He is also Director in Proton Beam Therapy Center, University of Tsukuba Hospital. He has been holding leadership, supervisory and administrative positions in particle therapy research in Japanese Society of Radiation Oncology (JASTRO), because he has been chair of particle therapy committee in JASTRO. In addition, brachytherapy, hyperthermia and boron neutron capture therapy are also his special interest. He has published over 500 articles on the basic research, translational medicine and clinical trial in radiation oncology.

Hideyuki Sakurai (Japan)
11:30 – 12:30 Discussion Forum 1: Liver Cancer
Topics: Motion Management, Hypofractionation, Multidisciplinary Care with Surgery and Systemic Therapy

Moderators: Chi-leung Chiang and Terence Tai-weng Sio
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Dr. Thomas Leung

Honorary Consultant in Medical Oncology
Director of the Clinical Trial Centre
Hong Kong Sanatorium and Hospital

Dr. Leung is currently Honorary Consultant in Medical Oncology, Director of the Clinical Trial Centre, at the Hong Kong Sanatorium and Hospital. He is also Honorary Associate Professor of the Department of Medicine in the Chinese University of Hong Kong. He was previously Professor in the Department of Clinical Oncology of Chinese University of Hong Kong until 2003 when he assumed the current position.
Dr. Leung has over 160 publications in peer-reviewed journals and 9 book chapters mainly on hepatocellular carcinoma (HCC), with a special focus on the management strategy in patients with advanced HCC and in the Asian population. Dr Leung also participated in various international consensus panels and gave recommendation on the use of systemic treatment, as well as the use Y-90 microspheres radioembolization. His research interests are non surgical treatment for advanced HCC.

Panelists: Hsiao-chieh Huang (Taiwan), Thomas Leung (Hong Kong SAR) and Hideyuki Sakurai (Japan)
12:30 – 14:00 Lunch Break
14:00 – 15:00 Session 2B (Clinical): Updates on Clinical Management
Moderators: Wai-tong Ng and Ru-xin Wong
Skull Base
Jonathan Ashman (USA)
Head and Neck
Lin Kong (China)
15:00 – 16:00 Discussion Forum 2: Head and Neck Cancer
Topics: Patients, Technique, Proton vs Carbon, Optimizing Systemic Therapy

Moderators: Chun-key Law and Yu-ming Wang
Panelists: Martin Bues (USA), Brigette Ma (Hong Kong)
16:00 – 16:30 Coffee Break, Exhibition and e-Poster Viewing
16:30 – 18:00 Session 3B (Clinical): Oral Presentation
Moderator: Warissara Rongthong
10:30 – 12:30 Session 1C (Clinical): Oral Presentation
Moderators: Amy Chang and Yang-gun Suh
12:30 – 14:00 Lunch Break
14:00 – 16:00 Session 2C: PTCOG-AO New Centres and Developments
Moderators: Tatsuya Ohno and Darren Ming-chun Poon
16:00 – 16:30 Coffee Break, Exhibition and e-Poster Viewing
16:30 – 18:00 Session 3C (Clinical): Oral Presentation
Moderator: Amy Chang